PGC1α gene Gly482Ser polymorphism predicts improved metabolic, inflammatory and vascular outcomes following bariatric surgery
نویسندگان
چکیده
منابع مشابه
Standardized outcomes reporting in metabolic and bariatric surgery.
ASMBS, SOARD, outcome reporting standards Standardized outcomes reporting in metabolic and bariatric surgery Stacy A. Brethauer, MD*, Julie Kim, MD, Maher el Chaar, MD, Pavlos Papasavas, MD, Dan Eisenberg, MD, Ann Rogers, MD, Naveen Ballem, MD, Mark Kligman, MD, Shanu Kothari, MD for the ASMBS Clinical Issues Committee Bariatric and Metabolic Center, Digestive Disease Institute, Cleveland Clini...
متن کامل[Maternal and fetal outcomes in pregnancy following bariatric surgery].
BACKGROUND Obesity is the most frequent metabolic disease in the World, and is associated with several comorbidities. Bariatric procedures arise as a promising treatment when classical approach is ineffective. Half of the operated patients are reproductive-aged women and there is evidence that obesity is related to worse maternal and fetal outcomes. Because nutritional status is affected by bar...
متن کاملThe Role of the PGC1α Gly482Ser Polymorphism in Weight Gain due to Intensive Diabetes Therapy
The Diabetes Control and Complications Trial (DCCT) involved intensive diabetes therapy of subjects with type 1 diabetes mellitus (T1DM) for an average period of 6.5 years. A subset of these subjects gained excessive weight. We tested for association of polymorphisms in 8 candidate genes with the above trait. We found the Gly482Ser polymorphism in the peroxisome proliferator-activated receptor ...
متن کاملCardiovascular Outcomes Improved by Bariatric Surgery Independent of Baseline BMI
Setting and participants. The Swedish Obese Subjects (SOS) trial is one of the largest and longest-running prospective trials of bariatric surgery in the world. Participants were enrolled between 1987 and 2001 from 480 Swedish primary health care centers. Individuals were eligible to participate if they were between 37 and 60 years of age and obese (minimum BMI of 34 for men and 38 for women) b...
متن کاملMechanisms of Diabetes Improvement Following Bariatric/Metabolic Surgery
More than 20 years ago, Pories et al. published a seminal article, "Who Would Have Thought It? An Operation Proves to Be the Most Effective Therapy for Adult-Onset Diabetes Mellitus." This was based on their observation that bariatric surgery rapidly normalized blood glucose levels in obese people with type 2 diabetes mellitus (T2DM), and 10 years later, almost 90% remained diabetes free. Porie...
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ژورنال
عنوان ژورنال: International Journal of Obesity
سال: 2011
ISSN: 0307-0565,1476-5497
DOI: 10.1038/ijo.2011.176